8/30/2023 0 Comments Download skin deep cosmetics![]() ![]() We hypothesized that the direct supplementation of the components that support the adjustment of the horny layer turnover rate is important for subjects with various types of skin conditions such as dry, oily, and sensitive skin. Thus, cosmetics containing essential components used to generate the horny layer, but not including ingredients not found on the skin such as surfactant, may be ideal products to improve the skin condition and quality of life (QOL) in subjects with hypofunction of the skin barrier. Rather, the replenishment of skin barrier components can lead to autonomous recovery of the skin barrier function. However, as the formation of the extracellular lipid lamellar membranes that contribute to the skin barrier function involves free fatty acids, ceramides, and cholesterol, 13 – 16 a mere supplementation of specific ingredients via cosmetics is not optimum skin care. Supplementation of moisturizing ingredients such as ceramide, natural moisturizing factor, and oil is one method used to improve the skin barrier function. Several studies have reported a relationship between sensitive and dry skin and hypofunction of the skin barrier. ![]() 1 – 7 The causes of reduced skin barrier function include a disturbance of the turnover cycle that creates a new horny layer and a deficiency of the moisturizing ingredients in the horny layer. It is thought that deterioration of the skin barrier function leads to uncomfortable conditions of the skin. In general, the skin barrier function is maintained by the horny layer, which consists of intercellular lipids, sebum, and corneocytes containing natural moisturizing factor.
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